Biomimetic magnetic Silk scaffold

Magnetic silk fibroin protein (SFP) scaffolds integrating
magnetic materials and featuring magnetic gradients were prepared for
potential utility in magnetic-field assisted tissue engineering. Magnetic
nanoparticles (MNPs) were introduced into SFP scaffolds via dip-coating
methods, resulting in magnetic SFP scaffolds with different strengths of
magnetization. Magnetic SFP scaffolds showed excellent hyperthermia
properties achieving temperature increases up to 8 °C in about 100 s.
The scaffolds were not toxic to osteogenic cells and improved cell
adhesion and proliferation. These findings suggest that tailored
magnetized silk-based biomaterials can be engineered with interesting
features for biomaterials and tissue-engineering applications.