Glucosamine and its N-acetyl-phenylalanine derivative prevent TNF-alpha-induced transcriptional activation in human chondrocytes
Articolo
Data di Pubblicazione:
2008
Abstract:
Glucosamine (GlcN) is used in the treatment of osteoarthritis as symptomatic slow-acting drug, but its mode of action is not completely known. We analyzed the influence of GlcN and its N-acetyl-phenylalanine derivative (NAPA) on mRNA transcription level of TNF-alpha-stimulated genes in cell culture.
Tipologia CRIS:
01.01 Articolo in rivista
Keywords:
CATHEPSIN-B; PROSTAGLANDIN E-2; NITRIC-OXIDE; OSTEOARTHRITIS; CARTILAGE
Elenco autori:
Giordano, CESARE GIOVANNI
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