Hyaluronan networking via Ugi's condensation using lysine as cross-linker diamine

A new type of hyaluronan based polymeric network has been prepared applying the well known cross-linking processes based on aqueous Ugi condensation reactions. In this study lysine has been used as a cross-linking agent.The structural and physico-chemical properties of the resulting hydrogels have been studied using solid state NMR spectroscopy and measurements of swelling in water and in aqueous NaCl solution.