A Grid-based SPM service (GriSPM) for SPECT and PET neurological studies.

Statistical parametric mapping (SPM) for the in-vivo
assessment of brain functional parameters in neurological
diseases is a voxel-based methodology used within the
nuclear medicine community to increase the confidence
level of diagnostic reporting. SPECT/PET SPM measurements
result in maps of statistically significant hypo-/
hyperfunctionality in cerebral regions of the patient with
respect to normal controls [1]. In general, voxel-based
assessments of changes in the functional signal allow earlier
and better diagnosis of neurological pathologies, which are
also less biased than qualitative visual inspection of images
or quantitative region-of-interest analysis