Gene expression profiles, a new dynamic and functional dimension to the exploration of learning and memory

Many experiments in the past have demonstrated the requirement of de novo
gene expression during the long-term retention of learning and memory.
Although previous studies implicated individual genes or genetic pathways
in learning and memory they did not uncover the collective behaviors of
the genes. In view of the broad variety of genes and the cross-talk of
genetic pathways, gene expression profiles offer a new dynamic and
functional dimension to the exploration of learning and memory. This
review illustrates how DNA microarray-based gene expression profiling may
help to dissect and analyze the complex mechanisms involved in gene
regulation during the acquisition and storage of memory.